Description

Terlipressin represents a synthetic analogue of vasopressin (antidiuretic hormone) designed with enhanced stability and prolonged duration of action compared to the native hormone. The compound incorporates specific modifications including N-terminal triglycyl substitution that provides resistance to enzymatic degradation and extends biological half-life. Terlipressin functions as a vasopressin receptor agonist with activity at both V1 (vascular) and V2 (renal) receptor subtypes, leading to vasoconstriction and antidiuretic effects respectively. The peptide demonstrates potent vasoconstrictor activity and has been extensively studied for its cardiovascular and renal effects in research models. Research applications include investigation of vasopressin biology, cardiovascular regulation mechanisms, fluid homeostasis, and the role of vasopressin signaling in various physiological and pathological processes. For research use only.