Description

Human Growth Hormone Fragment 191-176, more commonly referred to as Fragment 176-191, represents a specific 16-amino acid sequence derived from the C-terminal region of human growth hormone. The peptide exhibits the molecular formula C80H127N23O24S2 and corresponds to amino acids 176-191 of the complete 191-amino acid human growth hormone sequence. The fragment has earned designation as a ‘lipolytic fragment’ based on research demonstrating its ability to influence fat metabolism in laboratory systems. Studies have shown that Fragment 176-191 can stimulate lipolysis (the breakdown of stored fat) while simultaneously inhibiting lipogenesis (the formation of new fat tissue) in adipocyte culture systems. Research has indicated that Fragment 176-191 may influence adipocyte metabolism through multiple molecular pathways, potentially including modulation of beta-3 adrenergic receptors and effects on glycogen synthase phosphatase activity. For research use only.