Description

Sermorelin represents a synthetic analogue of the biologically active portion of human growth hormone-releasing hormone, specifically corresponding to the amino-terminal 1-29 amino acid sequence of endogenous GHRH. The compound exhibits the molecular formula C149H246N44O42S with a molecular weight of 3357.933 g/mol and is catalogued in PubChem under CID 16132413. This 29-amino acid peptide is considered the shortest fully functional fragment of GHRH, retaining complete biological activity for growth hormone stimulation. Sermorelin functions through specific binding to growth hormone-releasing hormone receptors, mimicking the action of native GHRH in stimulating growth hormone secretion. The peptide activates adenylyl cyclase through G-protein coupled receptor signaling, leading to increased cyclic adenosine monophosphate (cAMP) levels and subsequent growth hormone release. For research use only.