Description

Angiotensin II represents a key regulatory octapeptide in the renin-angiotensin system, demonstrating potent biological activity through specific binding to angiotensin receptors (AT1 and AT2). The compound plays central roles in cardiovascular regulation, blood pressure control, and fluid homeostasis mechanisms. The peptide consists of eight amino acids arranged in the sequence Asp-Arg-Val-Tyr-Ile-His-Pro-Phe, forming a highly active vasoconstrictor and regulatory hormone. Angiotensin II functions through G-protein coupled receptor activation, leading to various downstream signaling cascades that influence vascular tone, aldosterone secretion, and cardiovascular function. Research applications include investigation of cardiovascular physiology, hypertension mechanisms, and the molecular basis of angiotensin receptor signaling pathways. For research use only.