Description
This blend combines two synthetic growth hormone secretagogues that act at different receptors, for laboratory studies of GHRH receptor and ghrelin receptor signaling.
CJC-1295 NO DAC is the standard formulation of a synthetic growth hormone-releasing hormone analogue without the Drug Affinity Complex modification. It has the molecular formula C165H269N47O46 and a molecular weight of 3647.15 g/mol, and consists of 29 amino acids representing a modified version of the first 29 amino acids of GHRH. Its modifications include D-alanine at position 2 to resist enzymatic degradation, glutamine at position 8 to reduce asparagine rearrangement, alanine at position 15, and leucine at position 27 to prevent methionine oxidation.
Ipamorelin is a synthetic pentapeptide that acts as a selective agonist of the ghrelin receptor (GHS-R1a). It is used in research on ghrelin receptor signaling.
CJC-1295 NO DAC binds GHRH receptors, activating adenylyl cyclase and increasing cyclic AMP (cAMP) in laboratory systems. Ipamorelin activates the ghrelin receptor through a distinct G-protein coupled receptor pathway that also raises cAMP. Together they allow study of how GHRH and ghrelin receptor signaling interact in cell-based assays.
This formulation contains 5 mg of CJC-1295 NO DAC and 5 mg of Ipamorelin (10 mg total). Research preparations require appropriate reconstitution and storage to maintain the stability of both peptide components. Identity and purity are verified by third-party testing; see the Certificate of Analysis for this product.
For research use only. Not for human or veterinary use.

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