Description

Melanotan I represents a synthetic linear peptide developed as an analogue of α-melanocyte stimulating hormone, designed to investigate melanocortin receptor biology and pigmentation mechanisms. Unlike its cyclic counterpart Melanotan II, Melanotan I maintains a linear structure that provides different stability and receptor binding characteristics. The compound demonstrates melanocortin receptor binding activity with particular affinity for melanocortin-1 receptors, making it valuable for research examining melanocyte function and pigmentation pathways. The linear structure of Melanotan I allows for investigation of structure-activity relationships in melanocortin peptides and provides opportunities for studying the effects of peptide conformation on receptor binding and activation. Research applications include examination of melanocortin biology, pigmentation mechanisms, and the molecular basis of melanocyte regulation. For research use only.